Alerts

Isotonitazene- synthetic opioid more potent than fentanyl

1. Public Alert - N-Desethyl Isotonitazene

Xylazine - large animal tranquilizer mixed with fentanyl to prolong fentanyl action, no reversal agent, severe necrotic skin ulcerations

1. CDPH Alerts
1. CDPH Xylazine Information

   Basic information about xylazine, California’s action plan, and links to resources, including: Xylazine Wound Care Fact Sheet and other wound care links; webinar “Xylazine: An Introduction for Service Providers Working with Unhoused Individuals.

2. All Facilities Letter : Xylazine in the Illicit Drug Supply and Patient Practice
3. Issue Brief : Xylazine, Health Risks and Harm Reduction Strategies
4. March 2023 : Letter to Local Health Officers from CDPH and State Public Health Officer
5. California Health Alert Network (CAHAN): Xylazine in Illicit Fentanyl in the United States
2. 11-8-2022 FDA announcement
3. FDA letter to stakeholders
4. White House Action Plan